Pregnancy in sickle cell disease is at very high risk. Many reports have documented a considerable maternal risk of morbidity and mortality and high perinatal adverse outcomes. Previously, several systematic review and meta-analysis of previous observational studies, have quantified this risk. They showed that women with SCD have an increased risk of preeclampsia and maternal death, stillbirths, preterm deliveries, and small-for-gestational-age newborns.
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Case Study On Intrauterine Fetal Demise (Final Draft)
Case Study On Intrauterine Fetal Demise (Final Draft) | Uterus | Childbirth
Cohort and case-control methodologies are the main tools for analytical epidemiological research. Other important types of epidemiological studies mainly for generating hypotheses include cross-sectional and ecological, or correlation studies. The conclusions that can be drawn from findings of these types of studies are, however, much weaker compared to those of cohort and case-control studies. This is not to say that findings from cohort and case-control studies always reflect true associations which can be universally generalized. Epidemiological research is, to a large extent, of an observational character as opposed to experimental research. Experimental research provides data from which firmer conclusions can be made as compared with epidemiological studies. In experimental research, investigators can manipulate one factor while controlling others, and the main research question can be broken down into subquestions with comparatively simple causal assumptions
Perinatal outcome of placental massive perivillous fibrin deposition: a case-control study
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Stillbirth is typically defined as fetal death at or after 20 or 28 weeks of pregnancy , depending on the source. Often the cause is unknown. Worldwide prevention of most stillbirths is possible with improved health systems.