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Frontal lobe damage case study

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Phineas P. Historically, published accounts of Gage including scientific ones have almost always severely exaggerated and distorted his behavioral changes, frequently contradicting the known facts. A report of Gage's physical and mental condition shortly before his death implies that his most serious mental changes were temporary, so that in later life he was far more functional, and socially far better adapted, than in the years immediately following his accident. A social recovery hypothesis suggests that his work as a stagecoach driver in Chile fostered this recovery by providing daily structure that allowed him to regain lost social and personal skills. Physician John Martyn Harlow , who knew Gage before his accident, described him as "a perfectly healthy, strong and active young man, twenty-five years of age, nervo-bilious temperament, five feet six inches [1. Gage may have first worked with explosives on farms as a youth, or in nearby mines and quarries.
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Frontal lobe

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Nuclear medicine cases by study type and diagnosis

Phineas Gage was an American railroad construction foreman born in On September 13th, , when Gage was 25 years old, he was working in Cavendish in Vermont, leading a crew which were preparing the Rutland and Burlington Railroad by blasting rocks to make a roadbed. This was done by using an iron tamping rod to pack the explosive powder into a hole. The iron rod which was 43 inches long and 1. After the incident, Gage was thrown onto his back from the force of the iron rod and had some brief convulsion of the arms and legs. Within a few minutes however, Gage was able to get himself up, speak and walk with small assistance to a nearby cart so he could travel into town.
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A Guide to the Anatomy of the Brain

Frontal lobe deficiency, characterized by executive dysfunction such as deficits in attention and working memory, has been linked with an inability to abstain from alcohol. However, "high-functioning" alcoholics with frontal executive dysfunction may nonetheless appear to have a "normal" cognitive mental status. Findings from a new study using magnetic resonance imaging MRI to examine volumetric measurements of segmented brain structures suggest that executive function and general mental status are affected differently by long-term use of alcohol. They may get stuck in one response or one thought, showing inflexible behavior or thinking, or be unable to change their response when facing a new situation demanding a new or different direction.
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White matter WM mapping of the human brain using neuroimaging techniques has gained considerable interest in the neuroscience community. Using diffusion weighted DWI and magnetic resonance imaging MRI , WM fiber pathways between brain regions may be systematically assessed to make inferences concerning their role in normal brain function, influence on behavior, as well as concerning the consequences of network-level brain damage. In this paper, we investigate the detailed connectomics in a noted example of severe traumatic brain injury TBI which has proved important to and controversial in the history of neuroscience.
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